Caffeine Half-Life & Sleep Impact Calculator

Discover how caffeine lingers in your system, visualize its decay, and optimize your intake for better sleep. Supports multiple doses and personalized metabolism.

Caffeine half-life decay chart showing levels decreasing over time
Example caffeine decay curve over hours

Average: 5–6 hours. Smokers: ~3–4h. Pregnant: up to 10–12h.

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How Caffeine Affects Sleep

Caffeine blocks adenosine receptors in your brain, delaying sleepiness. Even after the buzz wears off, residual levels can disrupt sleep architecture — reducing deep REM stages and increasing nighttime awakenings. Studies from the Journal of Clinical Sleep Medicine show that 200mg of caffeine (about 2 coffees) taken 16 hours before bed can still impair sleep quality.

For optimal rest, aim for under 20mg at bedtime. Sensitive individuals (e.g., with insomnia or anxiety) may notice effects from as little as 10mg.

Chronic high intake can lead to tolerance, but sleep effects persist. Track your levels to find your ideal cutoff time.

Common Caffeine Sources

Know your doses to input accurately. Values are approximate — check labels for precision.

SourceCaffeine (mg)Serving
Coffee80–1008 oz brewed
Espresso631 shot (1 oz)
Black Tea40–708 oz
Green Tea20–458 oz
Energy Drink808 oz
Cola Soda30–4012 oz
Dark Chocolate20–301 oz
Caffeine Pill100–2001 pill

Real-Life Example: Daily Coffee Drinker

Suppose you have a 95mg coffee at 8 AM and another at 2 PM, with a 5.5-hour half-life and 10 PM bedtime.

At bedtime: ~15mg remaining (low impact). By 7 AM wake-up: <5mg. Adjust inputs above to simulate!

Factors Affecting Caffeine Half-Life

Your metabolism varies — here's a comparison:

GroupTypical Half-Life (hours)Why?
Average Adult5–6Standard liver enzyme activity.
Smokers3–4Nicotine speeds up metabolism.
Pregnant Women8–12Hormonal changes slow clearance.
Oral Contraceptive Users6–10Estrogen inhibits enzymes.
Liver Disease>10Reduced enzyme function.
Fast Metabolizers (Genetic)4–5CYP1A2 gene variant.

Source: Institute of Medicine, Caffeine for the Sustainment of Mental Task Performance.

Tips for Better Sleep & Caffeine Management

Optimize your routine to avoid sleep debt while enjoying caffeine's benefits.

Frequently Asked Questions

Why does half-life vary?

Genetics (CYP1A2 enzyme), pregnancy, liver function, smoking, and oral contraceptives all affect metabolism speed. Fast metabolizers clear it quicker; slow ones retain it longer.

Does food affect absorption?

Yes — consuming caffeine with meals can delay peak levels by 30–60 minutes but doesn't significantly alter total absorption or half-life.

When is the best cutoff time?

For most, no caffeine after 2–3 PM if bedtime is 10–11 PM. Use this tool to personalize based on your half-life and doses.

Can caffeine build up over days?

Yes, if consumed late and not fully cleared by morning. Chronic high intake leads to accumulation and tolerance.

How accurate is this calculator?

It's based on exponential decay models from pharmacology studies. Real levels vary by individual factors, but it's a solid estimate for planning.

Does exercise speed up clearance?

Lightly — physical activity may boost metabolism slightly, but not enough to rely on for late-day caffeine.

What about decaf?

Decaf has 2–15mg per cup — safe for evenings, but track if sensitive.

Can kids use this?

Children's half-life is similar (4–6h), but limit intake to <2.5mg/kg body weight daily per health guidelines.

Does age affect half-life?

Slightly — older adults may have 6–9h due to slower liver function.

How to find my exact half-life?

Genetic tests (e.g., 23andMe) reveal CYP1A2 variants, or experiment with timing and sleep tracking.

Reviewed by Health Expert • Updated January 2026 • Sources: Journal of Clinical Sleep Medicine, Institute of Medicine

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